Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells

Acrolein (Acr), a highly reactive unsaturated aldehyde, can cause various lung diseases including asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. We have found that Acr can damage not only genomic DNA but also DNA repair proteins causing repair dysfunction and enhancing cells’...

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Detalles Bibliográficos
Autores principales: Wang, Hsiang-Tsui, Lin, Jing-Heng, Yang, Chun-Hsiang, Haung, Chun-Hao, Weng, Ching-Wen, Maan-Yuh Lin, Anya, Lo, Yu-Li, Chen, Wei-Shen, Tang, Moon-Shong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642564/
https://www.ncbi.nlm.nih.gov/pubmed/29050289
http://dx.doi.org/10.18632/oncotarget.19710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642564/
https://www.ncbi.nlm.nih.gov/pubmed/29050289
http://dx.doi.org/10.18632/oncotarget.19710

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