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Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells

Cancer stem cells (CSCs) are associated with cancer recurrence following radio/chemotherapy owing to their high resistance to therapeutic intervention. In this study, we investigated the role of exostoxin 1 (EXT1), an endoplasmic reticulum (ER)-residing type II transmembrane glycoprotein, in cancer...

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Detalles Bibliográficos
Autores principales: Manandhar, Sarala, Kim, Chang-Gu, Lee, Sun-Hee, Kang, Soo Hyun, Basnet, Nikita, Lee, You Mie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642574/
https://www.ncbi.nlm.nih.gov/pubmed/29050299
http://dx.doi.org/10.18632/oncotarget.19737