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MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)

Obesity is associated with a wide range of metabolic disorders including inflammation and insulin-resistance. Sirtuin-1 (SIRT1) is an important regulator of metabolic homeostasis and stress response pathways in white adipose tissue. However, involvement of microRNAs (miRNAs) in regulating SIRT1 duri...

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Detalles Bibliográficos
Autores principales: Peng, Jie, Wu, Yinghui, Deng, Zhao, Zhou, Yuanfei, Song, Tongxing, Yang, Yang, Zhang, Xiaming, Xu, Tao, Xia, Mao, Cai, Anle, Liu, Zuhong, Peng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642576/
https://www.ncbi.nlm.nih.gov/pubmed/29050301
http://dx.doi.org/10.18632/oncotarget.19742