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2L-PCA: a two-level principal component analyzer for quantitative drug design and its applications

A two-level principal component predictor (2L-PCA) was proposed based on the principal component analysis (PCA) approach. It can be used to quantitatively analyze various compounds and peptides about their functions or potentials to become useful drugs. One level is for dealing with the physicochemi...

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Detalles Bibliográficos
Autores principales: Du, Qi-Shi, Wang, Shu-Qing, Xie, Neng-Zhong, Wang, Qing-Yan, Huang, Ri-Bo, Chou, Kuo-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642577/
https://www.ncbi.nlm.nih.gov/pubmed/29050302
http://dx.doi.org/10.18632/oncotarget.19757