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Interaction among CYP2C8, GPIIIa and P2Y12 variants increase susceptibility to ischemic stroke in Chinese population

PURPOSE: Genetic variants in cytochrome P450 (CYP), platelet membrane receptor (P2Y12, P2Y1), and glycoprotein IIIa (GPIIIa) genes are associated with the efficacy of clopidogrel and adverse clinical events on ischemic stroke (IS) patients. However, few studies have assessed whether gene-gene intera...

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Detalles Bibliográficos
Autores principales: Yi, Xingyang, Lin, Jing, Wang, Yanfen, Zhou, Ju, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642596/
https://www.ncbi.nlm.nih.gov/pubmed/29050321
http://dx.doi.org/10.18632/oncotarget.19991