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Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway

Colorectal cancer (CRC) is among the most common and fatal forms of solid tumors worldwide and more than two thirds of CRC and adenomas patients have APC gene mutations. APC is a key regulator in the Wnt/β-catenin signaling pathway but its roles in CRC remains to be elucidated. In this study, we com...

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Detalles Bibliográficos
Autores principales: Li, Fei-Feng, Zhao, Zhi-Xun, Yan, Peng, Wang, Song, Liu, Zheng, Zhang, Qiong, Zhang, Xiao-Ning, Sun, Chang-Hao, Wang, Xi-Shan, Wang, Gui-Yu, Liu, Shu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642601/
https://www.ncbi.nlm.nih.gov/pubmed/29050326
http://dx.doi.org/10.18632/oncotarget.20106