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Transcriptional downregulation of microRNA-19a by ROS production and NF-κB deactivation governs resistance to oxidative stress-initiated apoptosis

Cell apoptosis is one of the main pathological alterations during oxidative stress (OS) injury. Previously, we corroborated that nuclear factor-κB (NF-κB) transactivation confers apoptosis resistance against OS in mammalian cells, yet the underlying mechanisms remain enigmatic. Here we report that m...

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Detalles Bibliográficos
Autores principales: Hong, Jun, Wang, Ying, Hu, Bang-Chuan, Xu, Liang, Liu, Jing-Quan, Chen, Min-Hua, Wang, Jin-Zhu, Han, Fang, Zheng, Yang, Chen, Xu, Li, Qian, Yang, Xiang-Hong, Sun, Ren-Hua, Mo, Shi-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642611/
https://www.ncbi.nlm.nih.gov/pubmed/29050336
http://dx.doi.org/10.18632/oncotarget.20235