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Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

Epoxyeicosatrienoic acid (EET) production via cytochrome P450 (CYP) epoxygenases closely correlates with the progression of breast cancer. However, its role in the development of chemoresistant breast cancers has yet to be elucidated. Here, we found that CYP3A4 expression and its epoxy-product, 11,1...

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Detalles Bibliográficos
Autores principales: Thuy Phuong, Nguyen Thi, Kim, Ji Won, Kim, Jung-Ae, Jeon, Jang Su, Lee, Ji-Yoon, Xu, Wen Jun, Yang, Jin Won, Kim, Sang Kyum, Kang, Keon Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642617/
https://www.ncbi.nlm.nih.gov/pubmed/29050342
http://dx.doi.org/10.18632/oncotarget.20329