Cargando…
Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer
Epoxyeicosatrienoic acid (EET) production via cytochrome P450 (CYP) epoxygenases closely correlates with the progression of breast cancer. However, its role in the development of chemoresistant breast cancers has yet to be elucidated. Here, we found that CYP3A4 expression and its epoxy-product, 11,1...
Autores principales: | Thuy Phuong, Nguyen Thi, Kim, Ji Won, Kim, Jung-Ae, Jeon, Jang Su, Lee, Ji-Yoon, Xu, Wen Jun, Yang, Jin Won, Kim, Sang Kyum, Kang, Keon Wook |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642617/ https://www.ncbi.nlm.nih.gov/pubmed/29050342 http://dx.doi.org/10.18632/oncotarget.20329 |
Ejemplares similares
-
The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis
por: Kim, Hak Su, et al.
Publicado: (2021) -
11,12 Epoxyeicosatrienoic Acid Rescues Deteriorated Wound Healing in Diabetes
por: Sommer, Katharina, et al.
Publicado: (2021) -
11,12 and 14,15 epoxyeicosatrienoic acid rescue deteriorated wound healing in ischemia
por: Sommer, Katharina, et al.
Publicado: (2019) -
11,12‐Epoxyeicosatrienoic acid induces vasodilator response in the rat perfused mesenteric vasculature
por: Bihzad, S. M., et al.
Publicado: (2017) -
CYP2C19 Contributes to THP-1-Cell-Derived M2 Macrophage Polarization by Producing 11,12- and 14,15-Epoxyeicosatrienoic Acid, Agonists of the PPARγ Receptor
por: Cho, Hee Young, et al.
Publicado: (2023)