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MicroRNA-141-3p promotes glioma cell growth and temozolomide resistance by directly targeting p53

Glioblastoma multiforme is the most common primary malignancy in the brain and confers a uniformly poor prognosis. MicroRNAs have been shown to activate or inhibit tumorigenesis. Abnormalities in the p53 signaling pathway are found in various cancers and correlate with tumor formation. We examined t...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, Wu, Weining, Zeng, Ailiang, Nie, Er, Jin, Xin, Yu, Tianfu, Zhi, Tongle, Jiang, Kuan, Wang, Yingyi, Zhang, Junxia, You, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642619/
https://www.ncbi.nlm.nih.gov/pubmed/29050344
http://dx.doi.org/10.18632/oncotarget.20528