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Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management
Prostate cancer is a genetic disease. While next generation sequencing has allowed for the emergence of molecular taxonomy, classification is restricted to the nuclear genome. Mutations within the maternally inherited mitochondrial genome are known to impact cancer pathogenesis, as a result of distu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642640/ https://www.ncbi.nlm.nih.gov/pubmed/29050365 http://dx.doi.org/10.18632/oncotarget.19926 |