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Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management

Prostate cancer is a genetic disease. While next generation sequencing has allowed for the emergence of molecular taxonomy, classification is restricted to the nuclear genome. Mutations within the maternally inherited mitochondrial genome are known to impact cancer pathogenesis, as a result of distu...

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Detalles Bibliográficos
Autores principales: Kalsbeek, Anton M.F., Chan, Eva K.F., Corcoran, Niall M., Hovens, Christopher M., Hayes, Vanessa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642640/
https://www.ncbi.nlm.nih.gov/pubmed/29050365
http://dx.doi.org/10.18632/oncotarget.19926