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Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain

Kinesin1 plays a major role in neuronal transport by recruiting many different cargos through its kinesin light chain (KLC). Various structurally unrelated cargos interact with the conserved tetratricopeptide repeat (TPR) domain of KLC. The N-terminal capping helix of the TPR domain exhibits an atyp...

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Detalles Bibliográficos
Autores principales: Nguyen, The Quyen, Chenon, Mélanie, Vilela, Fernando, Velours, Christophe, Aumont-Nicaise, Magali, Andreani, Jessica, Varela, Paloma F., Llinas, Paola, Ménétrey, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642895/
https://www.ncbi.nlm.nih.gov/pubmed/29036226
http://dx.doi.org/10.1371/journal.pone.0186354