Cargando…

Aligner optimization increases accuracy and decreases compute times in multi-species sequence data

As sequencing technologies have evolved, the tools to analyze these sequences have made similar advances. However, for multi-species samples, we observed important and adverse differences in alignment specificity and computation time for bwa- mem (Burrows–Wheeler aligner-maximum exact matches) relat...

Descripción completa

Detalles Bibliográficos
Autores principales: Robinson, Kelly M., Hawkins, Aziah S., Santana-Cruz, Ivette, Adkins, Ricky S., Shetty, Amol C., Nagaraj, Sushma, Sadzewicz, Lisa, Tallon, Luke J., Rasko, David A., Fraser, Claire M., Mahurkar, Anup, Silva, Joana C., Dunning Hotopp, Julie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643015/
https://www.ncbi.nlm.nih.gov/pubmed/29114401
http://dx.doi.org/10.1099/mgen.0.000122