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Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma

Hepatitis B virus (HBV) is the dominant risk factor for hepatocellular carcinoma (HCC). HBV X protein (HBx) plays crucial roles in HCC carcinogenesis. HBx interferes with several signaling pathways including the Notch1 pathway in HCC. In this study, we found that Notch1 was highly expressed in HCC,...

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Detalles Bibliográficos
Autores principales: Liao, Bo, Zhou, Honghao, Liang, Huifang, Li, Changhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643068/
https://www.ncbi.nlm.nih.gov/pubmed/29048612
http://dx.doi.org/10.3892/ijo.2017.4126