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Dual action of NSC606985 on cell growth and apoptosis mediated through PKCδ in prostatic cancer cells

Chemotherapy is a vital therapeutic strategy for castration-resistant prostate cancer (CRPC). We have previously shown that NSC606985 (NSC), a camptothecin (CPT) analog, induced cell apoptosis via interacting with topoisomerase I (Topo I) in prostate cancer cells. In the present study, the effect an...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Tan, Chen, Wang, Guo, Cai, Jing-Jing, Wang, Li-Ping, Imperato-McGinley, Julianne, Zhu, Yuan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643069/
https://www.ncbi.nlm.nih.gov/pubmed/29048618
http://dx.doi.org/10.3892/ijo.2017.4138