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Dual action of NSC606985 on cell growth and apoptosis mediated through PKCδ in prostatic cancer cells
Chemotherapy is a vital therapeutic strategy for castration-resistant prostate cancer (CRPC). We have previously shown that NSC606985 (NSC), a camptothecin (CPT) analog, induced cell apoptosis via interacting with topoisomerase I (Topo I) in prostate cancer cells. In the present study, the effect an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643069/ https://www.ncbi.nlm.nih.gov/pubmed/29048618 http://dx.doi.org/10.3892/ijo.2017.4138 |