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Dual action of NSC606985 on cell growth and apoptosis mediated through PKCδ in prostatic cancer cells

Chemotherapy is a vital therapeutic strategy for castration-resistant prostate cancer (CRPC). We have previously shown that NSC606985 (NSC), a camptothecin (CPT) analog, induced cell apoptosis via interacting with topoisomerase I (Topo I) in prostate cancer cells. In the present study, the effect an...

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Detalles Bibliográficos
Autores principales:	Wang, Xin, Tan, Chen, Wang, Guo, Cai, Jing-Jing, Wang, Li-Ping, Imperato-McGinley, Julianne, Zhu, Yuan-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643069/ https://www.ncbi.nlm.nih.gov/pubmed/29048618 http://dx.doi.org/10.3892/ijo.2017.4138

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