A highly sensitive liquid chromatography electrospray ionization mass spectrometry method for quantification of TMA, TMAO and creatinine in mouse urine

Our method describes the quantification in mouse urine of trimethylamine (TMA), trimethylamine N-oxide (TMAO) and creatinine. The method combines derivatization of TMA, with ethyl bromoacetate, and LC chromatographic separation on an ACE C(18) column. The effluent was continuously electrosprayed int...

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Detalles Bibliográficos
Autores principales: Veeravalli, Sunil, Karu, Kersti, Phillips, Ian R., Shephard, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643081/
https://www.ncbi.nlm.nih.gov/pubmed/29062719
http://dx.doi.org/10.1016/j.mex.2017.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643081/
https://www.ncbi.nlm.nih.gov/pubmed/29062719
http://dx.doi.org/10.1016/j.mex.2017.09.004

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