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Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons

Burst spiking in substantia nigra pars compacta (SNc) dopaminergic neurons is a key signaling event in the circuitry controlling goal-directed behavior. It is widely believed that this spiking mode depends upon an interaction between synaptic activation of N-methyl-D-aspartate receptors (NMDARs) and...

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Detalles Bibliográficos
Autores principales: Galtieri, Daniel J, Estep, Chad M, Wokosin, David L, Traynelis, Stephen, Surmeier, D James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643088/
https://www.ncbi.nlm.nih.gov/pubmed/28980939
http://dx.doi.org/10.7554/eLife.30352