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Exploiting ecology in drug pulse sequences in favour of population reduction

A deterministic population dynamics model involving birth and death for a two-species system, comprising a wild-type and more resistant species competing via logistic growth, is subjected to two distinct stress environments designed to mimic those that would typically be induced by temporal variatio...

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Detalles Bibliográficos
Autores principales: Bauer, Marianne, Graf, Isabella R., Ngampruetikorn, Vudtiwat, Stephens, Greg J., Frey, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643144/
https://www.ncbi.nlm.nih.gov/pubmed/28957328
http://dx.doi.org/10.1371/journal.pcbi.1005747