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Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

BACKGROUND & AIMS: Crohn’s disease (CD) is a highly heritable disease that is particularly common in the Ashkenazi Jewish population. We studied 2 large Ashkenazi Jewish families with a high prevalence of CD in an attempt to identify novel genetic risk variants. METHODS: Ashkenazi Jewish patient...

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Detalles Bibliográficos
Autores principales: Levine, Adam P., Pontikos, Nikolas, Schiff, Elena R., Jostins, Luke, Speed, Doug, Lovat, Laurence B., Barrett, Jeffrey C., Grasberger, Helmut, Plagnol, Vincent, Segal, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643259/
https://www.ncbi.nlm.nih.gov/pubmed/27373512
http://dx.doi.org/10.1053/j.gastro.2016.06.040