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Long non-coding HCG18 promotes intervertebral disc degeneration by sponging miR-146a-5p and regulating TRAF6 expression

Intervertebral disc degeneration (IDD) is associated with the deterioration of nucleus pulposus (NP) cells due to hypertrophic differentiation and calcification. Emerging studies have shown that long noncoding RNAs (lncRNAs) play critical roles in the development of IDD. Using bioinformatics predict...

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Detalles Bibliográficos
Autores principales: Xi, Yanhai, Jiang, Tingwang, Wang, Weiheng, Yu, Jiangming, Wang, Yang, Wu, Xueming, He, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643303/
https://www.ncbi.nlm.nih.gov/pubmed/29038477
http://dx.doi.org/10.1038/s41598-017-13364-6