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Prokineticin receptor-1-dependent paracrine and autocrine pathways control cardiac tcf21(+) fibroblast progenitor cell transformation into adipocytes and vascular cells

Cardiac fat tissue volume and vascular dysfunction are strongly associated, accounting for overall body mass. Despite its pathophysiological significance, the origin and autocrine/paracrine pathways that regulate cardiac fat tissue and vascular network formation are unclear. We hypothesize that adip...

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Detalles Bibliográficos
Autores principales: Qureshi, Rehana, Kindo, Michel, Arora, Himanshu, Boulberdaa, Mounia, Steenman, Marja, Nebigil, Canan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643307/
https://www.ncbi.nlm.nih.gov/pubmed/29038558
http://dx.doi.org/10.1038/s41598-017-13198-2