Collision with duplex DNA renders Escherichia coli DNA polymerase III holoenzyme susceptible to DNA polymerase IV-mediated polymerase switching on the sliding clamp

Organisms possess multiple DNA polymerases (Pols) and use each for a different purpose. One of the five Pols in Escherichia coli, DNA polymerase IV (Pol IV), encoded by the dinB gene, is known to participate in lesion bypass at certain DNA adducts. To understand how cells choose Pols when the replic...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Thanh Thi, Furukohri, Asako, Tatsumi-Akiyama, Masahiro, Maki, Hisaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643309/
https://www.ncbi.nlm.nih.gov/pubmed/29038530
http://dx.doi.org/10.1038/s41598-017-13080-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643309/
https://www.ncbi.nlm.nih.gov/pubmed/29038530
http://dx.doi.org/10.1038/s41598-017-13080-1

Ejemplares similares