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A method to determine pharmacokinetic parameters based on andante constant-rate intravenous infusion
On account of the disturbance from the distribution phase, the concentration-time curve of drugs cannot fully reflect the characteristics of elimination, and thus, it is difficult for present methods to obtain ideal pharmacokinetic parameters. This paper presents a method to determine pharmacokineti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643313/ https://www.ncbi.nlm.nih.gov/pubmed/29038495 http://dx.doi.org/10.1038/s41598-017-13437-6 |