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Development of an athyroid mouse model using (131)I ablation after preparation with a low-iodine diet
We optimized the protocol for thyroid ablation in living mice using radioactive iodine (RAI) and a low-iodine diet (LID). To examine the effect of LID on thyroid ablation, mice were randomly divided into 4 groups: Vehicle, (131)I 2.775 MBq, (131)I 5.55 MBq, and LID + (131)I 2.775 MBq. The LID group...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643325/ https://www.ncbi.nlm.nih.gov/pubmed/29038462 http://dx.doi.org/10.1038/s41598-017-13772-8 |