The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway

The Hsp70 Ssb serves a dual role in de novo protein folding and ribosome biogenesis; however, the mechanism by which Ssb affects ribosome production is unclear. Here we establish that Ssb is causally linked to the regulation of ribosome biogenesis via the TORC1-Sch9 signaling pathway. Ssb is bound t...

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Detalles Bibliográficos
Autores principales: Mudholkar, Kaivalya, Fitzke, Edith, Prinz, Claudia, Mayer, Matthias P., Rospert, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643326/
https://www.ncbi.nlm.nih.gov/pubmed/29038496
http://dx.doi.org/10.1038/s41467-017-00635-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643326/
https://www.ncbi.nlm.nih.gov/pubmed/29038496
http://dx.doi.org/10.1038/s41467-017-00635-z

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