A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells

Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both residing in subcellular compartments including the mitochondrial electron tr...

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Detalles Bibliográficos
Autores principales: Elkis, Yoav, Cohen, Moshe, Yaffe, Etai, Satmary-Tusk, Shirly, Feldman, Tal, Hikri, Elad, Nyska, Abraham, Feiglin, Ariel, Ofran, Yanay, Shpungin, Sally, Nir, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643328/
https://www.ncbi.nlm.nih.gov/pubmed/29038547
http://dx.doi.org/10.1038/s41467-017-00832-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643328/
https://www.ncbi.nlm.nih.gov/pubmed/29038547
http://dx.doi.org/10.1038/s41467-017-00832-w

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