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A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells
Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both residing in subcellular compartments including the mitochondrial electron tr...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643328/ https://www.ncbi.nlm.nih.gov/pubmed/29038547 http://dx.doi.org/10.1038/s41467-017-00832-w |