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Rapid-Acting and Human Insulins: Hexamer Dissociation Kinetics upon Dilution of the Pharmaceutical Formulation

PURPOSE: Comparison of the dissociation kinetics of rapid-acting insulins lispro, aspart, glulisine and human insulin under physiologically relevant conditions. METHODS: Dissociation kinetics after dilution were monitored directly in terms of the average molecular mass using combined static and dyna...

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Detalles Bibliográficos
Autores principales: Gast, Klaus, Schüler, Anja, Wolff, Martin, Thalhammer, Anja, Berchtold, Harald, Nagel, Norbert, Lenherr, Gudrun, Hauck, Gerrit, Seckler, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643355/
https://www.ncbi.nlm.nih.gov/pubmed/28762200
http://dx.doi.org/10.1007/s11095-017-2233-0