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Rapid-Acting and Human Insulins: Hexamer Dissociation Kinetics upon Dilution of the Pharmaceutical Formulation
PURPOSE: Comparison of the dissociation kinetics of rapid-acting insulins lispro, aspart, glulisine and human insulin under physiologically relevant conditions. METHODS: Dissociation kinetics after dilution were monitored directly in terms of the average molecular mass using combined static and dyna...
Autores principales: | Gast, Klaus, Schüler, Anja, Wolff, Martin, Thalhammer, Anja, Berchtold, Harald, Nagel, Norbert, Lenherr, Gudrun, Hauck, Gerrit, Seckler, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643355/ https://www.ncbi.nlm.nih.gov/pubmed/28762200 http://dx.doi.org/10.1007/s11095-017-2233-0 |
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