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A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development

Zbtb16-encoded PLZF is a signature transcription factor (TF) that directs the acquisition of T-helper effector programs during the development of multiple innate lymphocyte lineages, including natural killer T cell, innate lymphoid cell, mucosal-associated invariant T cell and γδ lineages. PLZF is a...

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Detalles Bibliográficos
Autores principales: Mao, Ai-Ping, Ishizuka, Isabel E., Kasal, Darshan N., Mandal, Malay, Bendelac, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643357/
https://www.ncbi.nlm.nih.gov/pubmed/29038474
http://dx.doi.org/10.1038/s41467-017-00882-0