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Species differences in pancreatic binding of DO3A-VS-Cys(40)-Exendin4

AIMS: Radiolabeled Exendin-4 has been proposed as suitable imaging marker for pancreatic beta cell mass quantification mediated by Glucagon-like peptide-1 receptor (GLP-1R). However, noticeable species variations in basal pancreatic uptake as well as uptake reduction degree due to selective beta cel...

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Detalles Bibliográficos
Autores principales: Eriksson, Olof, Rosenström, Ulrika, Selvaraju, Ram K., Eriksson, Barbro, Velikyan, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643362/
https://www.ncbi.nlm.nih.gov/pubmed/28891030
http://dx.doi.org/10.1007/s00592-017-1046-2