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TC-PTP regulates the IL-7 transcriptional response during murine early T cell development

Cytokines play a critical role in directing the discrete and gradual transcriptional changes that define T cell development. The interleukin-7 receptor (IL-7R), via its activation of the JAK-STAT pathway, promotes gene programs that change dynamically as cells progress through T cell differentiation...

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Detalles Bibliográficos
Autores principales: Pike, K. A., Hatzihristidis, T., Bussières-Marmen, S., Robert, F., Desai, N., Miranda-Saavedra, D., Pelletier, J., Tremblay, M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643372/
https://www.ncbi.nlm.nih.gov/pubmed/29038451
http://dx.doi.org/10.1038/s41598-017-13673-w