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TC-PTP regulates the IL-7 transcriptional response during murine early T cell development
Cytokines play a critical role in directing the discrete and gradual transcriptional changes that define T cell development. The interleukin-7 receptor (IL-7R), via its activation of the JAK-STAT pathway, promotes gene programs that change dynamically as cells progress through T cell differentiation...
Autores principales: | Pike, K. A., Hatzihristidis, T., Bussières-Marmen, S., Robert, F., Desai, N., Miranda-Saavedra, D., Pelletier, J., Tremblay, M. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643372/ https://www.ncbi.nlm.nih.gov/pubmed/29038451 http://dx.doi.org/10.1038/s41598-017-13673-w |
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