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Genomics alterations of metastatic and primary tissues across 15 cancer types

Metastasis is an important event for cancer evolution and prognosis. In this article, we analyzed the differences in genomic alterations between primary and metastatic tissues at hotspot regions in 15 cancer types and 10,456 samples. Differential somatic mutations at the amino acid, protein domain a...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Zhan, Xiaohui, Dong, Chuanpeng, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643378/
https://www.ncbi.nlm.nih.gov/pubmed/29038591
http://dx.doi.org/10.1038/s41598-017-13650-3