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Gene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction

Vascular endothelial growth factor (VEGF) plays important roles in improvement of cardiac function following myocardial infarction (MI). However, the lack of a steerable delivery system of VEGF targeting the infarcted myocardium reduces the therapeutic efficacy and safety. Here, we constructed a ser...

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Detalles Bibliográficos
Autores principales: Xia, Jing-Bo, Wu, Hai-Yan, Lai, Bing-Lin, Zheng, Li, Zhou, Deng-Cheng, Chang, Zao-Shang, Mao, Cheng-Zhou, Liu, Guang-Hui, Park, Kyu-Sang, Zhao, Hui, Kim, Soo-Ki, Song, Guo-Hua, Cai, Dong-Qing, Qi, Xu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643404/
https://www.ncbi.nlm.nih.gov/pubmed/29038511
http://dx.doi.org/10.1038/s41598-017-13547-1