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Human rickettsial pathogen modulates arthropod organic anion transporting polypeptide and tryptophan pathway for its survival in ticks

The black-legged tick Ixodes scapularis transmits the human anaplasmosis agent, Anaplasma phagocytophilum. In this study, we show that A. phagocytophilum specifically up-regulates I. scapularis organic anion transporting polypeptide, isoatp4056 and kynurenine amino transferase (kat), a gene involved...

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Detalles Bibliográficos
Autores principales: Taank, Vikas, Dutta, Shovan, Dasgupta, Amrita, Steeves, Tanner K., Fish, Durland, Anderson, John F., Sultana, Hameeda, Neelakanta, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643405/
https://www.ncbi.nlm.nih.gov/pubmed/29038575
http://dx.doi.org/10.1038/s41598-017-13559-x