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Pharmacologic Targeting of Chromatin Modulators As Therapeutics of Acute Myeloid Leukemia
Acute myeloid leukemia (AML), a common hematological cancer of myeloid lineage cells, generally exhibits poor prognosis in the clinic and demands new treatment options. Recently, direct sequencing of samples from human AMLs and pre-leukemic diseases has unveiled their mutational landscapes and signi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643408/ https://www.ncbi.nlm.nih.gov/pubmed/29075615 http://dx.doi.org/10.3389/fonc.2017.00241 |