The P2X7 Receptor Mediates Toxoplasma gondii Control in Macrophages through Canonical NLRP3 Inflammasome Activation and Reactive Oxygen Species Production

Toxoplasma gondii (T. gondii) is the protozoan parasite that causes toxoplasmosis, a potentially fatal disease to immunocompromised patients, and which affects approximately 30% of the world’s population. Previously, we showed that purinergic signaling via the P2X7 receptor contributes to T. gondii...

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Detalles Bibliográficos
Autores principales: Moreira-Souza, Aline Cristina Abreu, Almeida-da-Silva, Cássio Luiz Coutinho, Rangel, Thuany Prado, Rocha, Gabrielle da Costa, Bellio, Maria, Zamboni, Dario Simões, Vommaro, Rossiane Claudia, Coutinho-Silva, Robson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643413/
https://www.ncbi.nlm.nih.gov/pubmed/29075257
http://dx.doi.org/10.3389/fimmu.2017.01257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643413/
https://www.ncbi.nlm.nih.gov/pubmed/29075257
http://dx.doi.org/10.3389/fimmu.2017.01257

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