BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Receptors

Brain-derived neurotrophic factor (BDNF) is a key regulator of neuronal plasticity and cognitive functions. BDNF val66met polymorphism, a human single-nucleotide polymorphism (SNP) in the pro-domain of BDNF gene, is associated with deficits in activity-dependent BDNF secretion and hippocampus-depend...

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Detalles Bibliográficos
Autores principales: Hao, Rui, Qi, Yu, Hou, Dong-Ni, Ji, Yuan-Yuan, Zheng, Chun-Yan, Li, Chu-Yu, Yung, Wing-Ho, Lu, Bai, Huang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643500/
https://www.ncbi.nlm.nih.gov/pubmed/29075179
http://dx.doi.org/10.3389/fncel.2017.00306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643500/
https://www.ncbi.nlm.nih.gov/pubmed/29075179
http://dx.doi.org/10.3389/fncel.2017.00306

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