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Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas

Circulating tumor cells (CTCs) play a major role in the metastasis and recurrence of hepatocellular carcinoma (HCC). Here, we found that major vault protein (MVP) is expressed on the surface of HCC cells and further induced under stressful environments. MVP knockdown reduces cell proliferation and i...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Min, Joh, Jae Won, Seo, Se-Ri, Kim, Won-Tae, Kim, Min Kyu, Choi, Hong Seo, Kim, So Young, Jang, Young-Joo, Sinn, Dong Hyun, Choi, Gyu Seong, Kim, Jong Man, Kwon, Choon Hyuck David, Chang, Hee Jin, Kim, Dae Shick, Ryu, Chun Jeih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643512/
https://www.ncbi.nlm.nih.gov/pubmed/29038587
http://dx.doi.org/10.1038/s41598-017-13501-1