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Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

Chronic liver disease is rising in western countries and liver cirrhosis is the 12th leading cause of death worldwide. Simultaneously, use of gastric acid suppressive medications is increasing. Here, we show that proton pump inhibitors promote progression of alcoholic liver disease, non-alcoholic fa...

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Detalles Bibliográficos
Autores principales: Llorente, Cristina, Jepsen, Peter, Inamine, Tatsuo, Wang, Lirui, Bluemel, Sena, Wang, Hui J., Loomba, Rohit, Bajaj, Jasmohan S., Schubert, Mitchell L., Sikaroodi, Masoumeh, Gillevet, Patrick M., Xu, Jun, Kisseleva, Tatiana, Ho, Samuel B., DePew, Jessica, Du, Xin, Sørensen, Henrik T., Vilstrup, Hendrik, Nelson, Karen E., Brenner, David A., Fouts, Derrick E., Schnabl, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643518/
https://www.ncbi.nlm.nih.gov/pubmed/29038503
http://dx.doi.org/10.1038/s41467-017-00796-x