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A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response
While the physiological benefits of the fibroblast growth factor 21 (FGF21) hepatokine are documented in response to fasting, little information is available on Fgf21 regulation in a glucose-overload context. We report that peroxisome-proliferator-activated receptor α (PPARα), a nuclear receptor of...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643524/ https://www.ncbi.nlm.nih.gov/pubmed/29020627 http://dx.doi.org/10.1016/j.celrep.2017.09.065 |