A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

While the physiological benefits of the fibroblast growth factor 21 (FGF21) hepatokine are documented in response to fasting, little information is available on Fgf21 regulation in a glucose-overload context. We report that peroxisome-proliferator-activated receptor α (PPARα), a nuclear receptor of...

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Detalles Bibliográficos
Autores principales: Iroz, Alison, Montagner, Alexandra, Benhamed, Fadila, Levavasseur, Françoise, Polizzi, Arnaud, Anthony, Elodie, Régnier, Marion, Fouché, Edwin, Lukowicz, Céline, Cauzac, Michèle, Tournier, Emilie, Do-Cruzeiro, Marcio, Daujat-Chavanieu, Martine, Gerbal-Chalouin, Sabine, Fauveau, Véronique, Marmier, Solenne, Burnol, Anne-Françoise, Guilmeau, Sandra, Lippi, Yannick, Girard, Jean, Wahli, Walter, Dentin, Renaud, Guillou, Hervé, Postic, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643524/
https://www.ncbi.nlm.nih.gov/pubmed/29020627
http://dx.doi.org/10.1016/j.celrep.2017.09.065

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