The Bacteroidales produce an N-acylated derivative of glycine with both cholesterol-solubilising and hemolytic activity

The contribution of the gut microbiota to the metabolism of cholesterol is not well understood. In this study, we identify 21 fosmid clones from a human gut microbiome metagenomic library that, when expressed in Escherichia coli, produce halos on LB agar supplemented with 0.01% (w/v) cholesterol (LB...

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Detalles Bibliográficos
Autores principales: Lynch, Alli, Crowley, Elaine, Casey, Eoghan, Cano, Rafael, Shanahan, Rachel, McGlacken, Ger, Marchesi, Julian R., Clarke, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643525/
https://www.ncbi.nlm.nih.gov/pubmed/29038461
http://dx.doi.org/10.1038/s41598-017-13774-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643525/
https://www.ncbi.nlm.nih.gov/pubmed/29038461
http://dx.doi.org/10.1038/s41598-017-13774-6

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