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The Bacteroidales produce an N-acylated derivative of glycine with both cholesterol-solubilising and hemolytic activity
The contribution of the gut microbiota to the metabolism of cholesterol is not well understood. In this study, we identify 21 fosmid clones from a human gut microbiome metagenomic library that, when expressed in Escherichia coli, produce halos on LB agar supplemented with 0.01% (w/v) cholesterol (LB...
Autores principales: | Lynch, Alli, Crowley, Elaine, Casey, Eoghan, Cano, Rafael, Shanahan, Rachel, McGlacken, Ger, Marchesi, Julian R., Clarke, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643525/ https://www.ncbi.nlm.nih.gov/pubmed/29038461 http://dx.doi.org/10.1038/s41598-017-13774-6 |
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