Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme

Enzymes dependent on pyridoxal 5′-phosphate (PLP, the active form of vitamin B(6)) perform a myriad of diverse chemical transformations. They promote various reactions by modulating the electronic states of PLP through weak interactions in the active site. Neutron crystallography has the unique abil...

Descripción completa

Detalles Bibliográficos
Autores principales: Dajnowicz, Steven, Johnston, Ryne C., Parks, Jerry M., Blakeley, Matthew P., Keen, David A., Weiss, Kevin L., Gerlits, Oksana, Kovalevsky, Andrey, Mueser, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643538/
https://www.ncbi.nlm.nih.gov/pubmed/29038582
http://dx.doi.org/10.1038/s41467-017-01060-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643538/
https://www.ncbi.nlm.nih.gov/pubmed/29038582
http://dx.doi.org/10.1038/s41467-017-01060-y

Ejemplares similares