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Transmembrane Segment XI of the Na(+)/H(+) Antiporter of S. pombe is a Critical Part of the Ion Translocation Pore

The Na(+)/H(+) exchanger of the plasma membrane of S. pombe (SpNHE1) removes intracellular sodium in exchange for an extracellular proton. We examined the structure and functional role of amino acids 360–393 of putative transmembrane (TM) segment XI of SpNHE1. Structural analysis suggested that it h...

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Detalles Bibliográficos
Autores principales: Dutta, Debajyoti, Shin, Kyungsoo, Rainey, Jan K., Fliegel, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643542/
https://www.ncbi.nlm.nih.gov/pubmed/29038548
http://dx.doi.org/10.1038/s41598-017-12701-z