Cargando…

Transmembrane Segment XI of the Na(+)/H(+) Antiporter of S. pombe is a Critical Part of the Ion Translocation Pore

The Na(+)/H(+) exchanger of the plasma membrane of S. pombe (SpNHE1) removes intracellular sodium in exchange for an extracellular proton. We examined the structure and functional role of amino acids 360–393 of putative transmembrane (TM) segment XI of SpNHE1. Structural analysis suggested that it h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dutta, Debajyoti, Shin, Kyungsoo, Rainey, Jan K., Fliegel, Larry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643542/ https://www.ncbi.nlm.nih.gov/pubmed/29038548 http://dx.doi.org/10.1038/s41598-017-12701-z

Ejemplares similares

Functional Analysis of Conserved Transmembrane Charged Residues and a Yeast Specific Extracellular Loop of the Plasma Membrane Na(+)/H(+) Antiporter of Schizosaccharomyces pombe
por: Dutta, Debajyoti, et al.
Publicado: (2019)

Amino Acids 563–566 of the Na(+)/H(+) Exchanger Isoform 1 C-Terminal Cytosolic Tail Prevent Protein Degradation and Stabilize Protein Expression and Activity
por: Li, Xiuju, et al.
Publicado: (2020)

Rainbow Trout (Oncorhynchus mykiss) Na(+)/H(+) Exchangers tNhe3a and tNhe3b Display Unique Inhibitory Profiles Dissimilar from Mammalian NHE Isoforms
por: Blair, Salvatore, et al.
Publicado: (2021)

Basolateral Na(+)-H+ antiporter. Mechanisms of electroneutral and conductive ion transport
Publicado: (1994)

The Na(+)/H(+) exchanger in metastasis
por: Amith, Schammim Ray, et al.
Publicado: (2016)

Characterization of the Na(+)/H(+) Antiporter from Yersinia pestis
por: Ganoth, Assaf, et al.
Publicado: (2011)

Structural and Functional Changes in the Na(+)/H(+) Exchanger Isoform 1, Induced by Erk1/2 Phosphorylation
por: Fliegel, Larry
Publicado: (2019)

Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe
por: Varberg, Joseph M, et al.
Publicado: (2022)

Modulating the Chemical Transport Properties of a Transmembrane Antiporter via Alternative Anion Flux
por: Wang, Zhi, et al.
Publicado: (2018)

Computational Design of Transmembrane Pores
por: Xu, Chunfu, et al.
Publicado: (2020)

Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe
por: Asakawa, Haruhiko, et al.
Publicado: (2014)

Promiscuous Binding in a Selective Protein: The Bacterial Na(+)/H(+) Antiporter
por: Alhadeff, Raphael, et al.
Publicado: (2011)

Electrogenic Cation Binding in the Electroneutral Na(+)/H(+) Antiporter of Pyrococcus abyssi
por: Călinescu, Octavian, et al.
Publicado: (2016)

A Novel Human Mutation in the SLC9A1 Gene Results in Abolition of Na(+)/H(+) Exchanger Activity
por: Li, Xiuju, et al.
Publicado: (2015)

Ion Binding and Selectivity of the Na(+)/H(+) Antiporter MjNhaP1 from Experiment and Simulation
por: Warnau, Judith, et al.
Publicado: (2019)

Desensitization by external Na of the cyclic AMP-dependent Na+/H+ antiporter in trout red blood cells
Publicado: (1988)

Hæmatological Technique. Part XI
por: Napier, L. Everard, et al.
Publicado: (1941)

The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope
Publicado: (1992)

Molecular Characterization of the Na(+)/H(+)-Antiporter NhaA from Salmonella Typhimurium
por: Lentes, Christopher J., et al.
Publicado: (2014)

NhaA Na(+)/H(+) Antiporter Mutants That Hardly React to the Membrane Potential
por: Alkoby, Dudu, et al.
Publicado: (2014)

Characterization of Two Na(+)(K(+), Li(+))/H(+) Antiporters from Natronorubrum daqingense
por: Wang, Qi, et al.
Publicado: (2023)

Confined Dynamics of Water in Transmembrane Pore of TRPV1 Ion Channel
por: Trofimov, Yury A., et al.
Publicado: (2019)

Assessing Na(+)/H(+) exchange and cell effector functionality in metastatic breast cancer
por: Amith, Schammim Ray, et al.
Publicado: (2016)

Na(+)-H+ antiport detected through hydrogen ion currents in rat alveolar epithelial cells and human neutrophils
Publicado: (1994)

Transmembrane helical interactions in the CFTR channel pore
por: Das, Jhuma, et al.
Publicado: (2017)

Cytoplasmic pH regulation in thymic lymphocytes by an amiloride- sensitive Na+/H+ antiport
Publicado: (1984)

Correction: NhaA Na(+)/H(+) Antiporter Mutants That Hardly React to the Membrane Potential
Publicado: (2014)

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na(+)/H(+) antiporters
por: Landreh, Michael, et al.
Publicado: (2017)

Architecture and autoinhibitory mechanism of the plasma membrane Na(+)/H(+) antiporter SOS1 in Arabidopsis
por: Wang, Yuhang, et al.
Publicado: (2023)

Commentary Cystic Fibrosis Transmembrane Conductance Regulator : Permeant Ions Find the Pore
por: Dawson, David C., et al.
Publicado: (1997)

Ion access pathway to the transmembrane pore in P2X receptor channels
por: Kawate, Toshimitsu, et al.
Publicado: (2011)

Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
por: Wang, Wuyang, et al.
Publicado: (2011)

Spatial positioning of CFTR’s pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway
por: Gao, Xiaolong, et al.
Publicado: (2016)

Stop Codon Polymorphisms in the Human SLC9A1 Gene Disrupt or Compromise Na(+)/H(+) Exchanger Function
por: Li, Xiuju, et al.
Publicado: (2016)

Detecting pore-lining regions in transmembrane protein sequences
por: Nugent, Timothy, et al.
Publicado: (2012)

Assembly of transmembrane pores from mirror-image peptides
por: Krishnan R, Smrithi, et al.
Publicado: (2022)

Polymer Translocation through Nanometer Pores
por: Paun, Maria-Alexandra, et al.
Publicado: (2022)

Functional comparison of plasma-membrane Na(+)/H(+ )antiporters from two pathogenic Candida species
por: Krauke, Yannick, et al.
Publicado: (2008)

Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells
Publicado: (1986)

The Deactive Form of Respiratory Complex I from Mammalian Mitochondria Is a Na(+)/H(+) Antiporter
por: Roberts, Philippa G., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2c2depev8s904btrb0bhvshmk1